DNA double-strand break processing: the beginning of the end
نویسندگان
چکیده
منابع مشابه
DNA double-strand break processing: the beginning of the end.
Nucleolytic processing of DNA double-strand breaks (DSBs) generates 3' ssDNA tails that are essential for the assembly of DNA damage checkpoint signaling and DNA repair protein complexes. Genetic studies have provided evidence that multiple nuclease activities are involved in DSB end resection. Three recent studies, including work by Jackson and colleagues (pp. 2767- 2772) in the October 15, 20...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2008
ISSN: 0890-9369
DOI: 10.1101/gad.1742408